Focus on human microbiome to fight liver cirrhosis
22 European institutions join forces in MICROB-PREDICT to improve the prevention and treatment of chronic liver disease (cirrhosis). We aim to identify microbiome-based biomarkers and mechanisms that predict in advance when the body can no longer compensate for the dysfunctional liver (decompensated cirrhosis), when such decompensated cirrhosis will progress to acute-on-chronic liver failure (ACLF), and a patient’s individual treatment response. Based on such biomarkers, we strive to develop novel diagnostic tools for earlier and better patient stratification and to establish personalised and effective treatment strategies.
Data Hub
Contact
Privacy Policy15th Steering Committee Meeting: Strong momentum!
The 15th MICROB-PREDICT Steering Committee (SC) Meeting was held online over two highly productive days to review the progress across all work packages, including clinical and genetic characterisation, ALB-TRIAL progress, microbiome research, multi-omics integration, experimental validation and systems modelling. The depth and quality of the discussions highlighted major advances in proteomics, metabolomics, biomarker validation, and predictive modelling, underlining the strength of the project’s multidisciplinary collaboration. The meeting took place in a period of shared grief following the sudden passing of WP2 leader Peer Bork (EMBL). Overall, the meeting confirmed the project’s strong momentum and collective commitment to delivering high-quality results and tangible innovations in line with the project’s objectives and obligations to the European Commission.
More newsIn memoriam: Prof. Peer Bork dies at 62
It is with great sadness that we announce the sudden passing of Prof. Peer Bork, EMBL Interim Director General. He passed away last Friday, 16 January 2026, during a business trip to a conference in Taiwan. We grieve alongside his family and extend our warmest condolences, while remembering a wonderful person, a dedicated mentor, and an unforgettable scientist. Within the MICROB-PREDICT consortium, he was a pivotal team leader who motivated and inspired colleagues and mentees alike, contributed a widely recognised masterclass lecture, and enabled the analysis of a vast variety of microbiome samples (WP2). His exceptional leadership, outstanding scientific achievements, and inspiring spirit will live on forever. Thank you for everything, Peer!
More newsMICROB-PREDICT project video
Focus on human microbiome to fight liver cirrhosis: 22 European institutions joined forces in January 2019 to improve the prevention and treatment of chronic liver disease (cirrhosis) within the MICROB-PREDICT project. We aim to identify microbiome-based biomarkers and mechanisms that predict in advance when the body can no longer compensate for the dysfunctional liver (decompensated cirrhosis) and decompensated cirrhosis progresses to acute-on-chronic liver failure (ACLF), and individual treatment responses of patients. Coordinator Jonel Trebicka gives a brief overview of the project in this video.
More news