Recent developments, presentations, awards & more

Project News

This section keeps you updated on any major developments throughout the course of the MICROB-PREDICT project. For PDFs of our own press releases about progress within the MICROB-PREDICT project please go to DOWNLOADS. To receive our project newsletter please subscribe here!

  • 2 September 2021

    Successful MICROB-PREDICT Online Symposium connected to EASL School on Hepatology 2021

    Successful MICROB-PREDICT and DECISION – Online Symposium ‘Management of acute-on-chronic liver failure’ on Thursday, 2nd September 2021 from 12.30 – 16.30h CEST which was organised at the occasion of the EASL School of Hepatology.

    At this symposium, several experts of both project consortia presented recent advances in the fields of microbiome research and systems medicine, introduced the role of proteomics and metabolomics in hepatology and discussed treatment strategies and their mechanisms of action in acute-on-chronic liver failure.

    With almost 100 registered attendees and speakers from 37 countries our symposium was a great success and we would like to thank everyone for their participation and the lively discussions.

  • 8 July 2021

    MICROB-PREDICT Symposium connected to EASL School on Hepatology 2021

    We would like to invite you for the MICROB-PREDICT online symposium on ‘Management of acute-on-chronic liver failure’, which will take place on 2nd September 2021, in the afternoon before the EASL School of Hepatology.

    Course director: Prof. Wim Laleman

    Date: Thursday, 02 September 2021


    Read full announcement

  • 29 June 2021

    MICROB-PREDICT project partners at the IHMC 2021

    We are pleased that four of our MICROB-PREDICT project partners gave a talk at this year’s virtual International Human Microbiome Consortium Congress 2021 (IHMC 2021), which took place from June 27-29, 2021.

    Sunday, 27th June

    1.30 PM (CEST): Stanislav Dusko Ehrlich – ‘Oral Microbiome in Health and Disease

    Monday, 28th June

    12.30 PM (CEST): Peer Bork – ‘The Impact of Drugs on Human Gut Microbial Communities

    6.15 PM (CEST): Mani Arumugam – ‘Revealing the Hidden Biodiversity of the Human Gut Microbiota

    Tuesday, 29th June

    12.30 PM (CEST): Jonel Trebicka – ‘Gut Microbiome and End-Stage Liver Disease

  • 24 June 2021

    ILC 2021: Symposium „Old and new treatments for patients with advanced cirrhosis”

    Very successful symposium on Thursday, 24th June 2021 from 14-15h CEST organised by members of MICROB-PREDICT in the frame of the virtual ILC congress. Topics included:

    • Why and how to modulate the microbiome: example from MICROB-PREDICT study (Shawcross)
    • Old drugs for novel treatment strategies (Posé)
    • Human albumin: from established indications to novel perspectives (Caraceni)
    • System medicine: is it the right track to personalized treatments: example from DECISION study? (Trebicka)

  • 10 June 2021

    MICROB-PREDICT at the International Liver Congress 2021!

    SAVE THE DATE: ILC 2021 will take place from Wednesday to Saturday, 23–26 June. Register now and visit our MICROB-PREDICT booth.

    Click here for more information!

  • 9 June 2021

    Successful patient event on 9th June

    27 representatives of national patient organisations from 10 European countries listened to talks about therapies for cirrhosis and ACLF, research needs and outlook for the future. A lot of interest was shown towards available and new therapies for decompensated cirrhosis and ACLF. The event was organised by ELPA (president Marko Korenjak) and chaired by Prof. Rajiv Jalan, scientific director of EFCLIF.

  • 11 May 2021

    Workshop on “Health and economic benefits of microbiomes” with the EU Parliament

    MicrobiomeSupport is organising an online workshop with the Panel for the Future of Science and Technology (STOA) at the European Parliament. This virtual event will, among other things, present state-of-the-art microbiome research and address safety and regulatory pathways of microbiome innovations. The workshop will take place virtually on 11th May 2021, between 14:00 and 16:30 CEST.

    For further information and registration, click here.

  • 5 May 2021

    Article on “Microbiome and Nanotechnology” got frontispiece of Advanced Materials

    Congratulations to Arben Merkoçi and co‐workers, whose article on “Microbiome and Nanotechnology: The Microbiome Meets Nanotechnology: Opportunities and Challenges in Developing New Diagnostic Devices” got frontispiece of Advanced Materials (Adv. Mater. 18/2021). In this article, Arben and his team consider the unique properties of nanomaterials that will enable, in the near future, the development of point‐of‐care sensors for the detection of microbiome‐related biomarkers. Read full article.

  • 1 February 2021

    Annelotte Broekhoven appointed as new chair of the Early Career Scientists group

    We congratulate Annelotte Broekhoven from Leiden University Medical Center for having been appointed as new chair of the MICROB-PREDICT Early Career Scientists group. She takes this important position over from her predecessor Romy Zwittink (also LUMC) who was the chair in the second year of the project, after Robert Schierwagen from Goethe University Frankfurt, who successfully filled this role in the first year. It will be Annelotte`s task to coordinate the training activities during the 3rd year which include amongst other things the organisation of the 2nd masterclass.

  • 25 January 2021

    5th Steering Committee Meeting held online

    20 members of the MICROB-PREDICT Steering Committee met online on 25-26 January to discuss first multiomics and very interesting animal results. Corona slowed things down in 2020, but the project is still progressing very well thanks to the amazing work of all our 22 partner institutions and about 100 involved scientists.

  • 30 November 2020

    Nature Reviews: Utilizing the gut microbiome in decompensated cirrhosis and acute- on- chronic liver failure

    Read the latest nature reviews article which focuses on the possible pathogenic, diagnostic and therapeutic role of the gut microbiome in decompensation of cirrhosis and progression to ACLF by Jonel Trebicka, Peer Bork, Aleksander Krag and Manimozhiyan Arumugam. Read more.

  • 19 November 2020

    PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis

    Proven bacterial infections and severe alcoholic hepatitis, alone or in combination, are the major precipitating events for acute decompensation and ACLF. While the type of precipitating event has no association with survival, the number of identifiable events was significantly associated with surrogates of systemic inflammation and increased 90-day mortality. Adequate first-line antibiotic treatment of proven bacterial infections was associated with lower ACLF development rate and higher 90-day survival. Specific preventive and therapeutic strategies to precipitating events may improve outcome in decompensated cirrhosis. Read more.

  • 19 October 2020

    Targeting the gut-liver-immune axis to treat cirrhosis

    Thomas Tranah and colleagues from King`s College London publish a review about links between cirrhotic dysbiosis, intestinal barrier dysfunction and deficits of host-microbiome compartmentalisation and mucosal immune homoeostasis that occur in settings of advanced chronic liver disease. Read more.

  • 2 October 2020

    New MICROB-PREDICT Masterclass video on „The human gut microbiome in health and disease” by Prof. Peer Bork

    Prof. Peer Bork’s speaks about the latest advances in microbiome research as part of the MICROB-PREDICT project. The talk was recorded at the occasion of the first MICROB-PREDICT MasterClass in Frankfurt.

  • 18 September 2020

    Funding from The Michael J. Fox Foundation

    Fantastic news: MICROB-PREDICT partners were awarded 8.2m USD funding from The Michael J. Fox Foundation for research into the Genome-Microbiome Axis in the Cause of Parkinson Disease. Read more

  • 3 September 2020

    Paper by Olaf Tyc et al. published on the cover page of Liver transplantation

    Congratulations to Olaf and co-workers! The article on “Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease” by Olaf Tyc et al. made it to the cover page of Liver transplantation (Volume 26, Issue 12). Congratulations to all for the great achievement! Read full article.

  • 27 August 2020

    Who are the people behind the science of MICROB-PREDICT?

    Watch this video to meet the coordinator, the patient representative, our leading researchers, clinicians, and the management team. Feel free to like and share to promote our research and efforts. We are all working together to improve the lives of patients suffering from decompensated cirrhosis and ACLF.

  • 26 August 2020

    MICROB-PREDICT in 3 minutes – Prof. Dr. Jonel Trebicka summarises the project at EASL’s “Digital ILC 2020”

    As part of the DigitalILC, the project’s scientific coordinator, Prof. Dr. Jonel Trebicka recorded this brief webinar to give a concise overview of the project’s scope, its aims, and the expected patient benefits. Click here to watch the video!

  • 14 July 2020

    The PREDICT study uncovers three clinical courses in acutely decompensated cirrhosis with distinct pathophysiology

    Data from 1071 patients with acute decompensation reveals patterns that allow grouping patients into three different clinical courses with different mortality. The investigators have determined that the development of systemic inflammation is key to the progression of the disease and affects patients with pre-ACLF. Half of them die in three months and seven out of ten in 1 year. Read more.

  • 10 July 2020

    Marko Korenjak is being interviewed about MICROB-PREDICT by Maja Thiele

    Former “radio moderator”-turned-“medical hepatologist” Prof. Dr. Maja Thiele from Odense University Hospital (OUH) in Denmark interviews Marko Korenjak, the current president of the European Liver Patients’ Association (ELPA) about his hopes in MICROB-PREDICT and why this is such a special research consortium. Watch and share the whole 5min-video on YouTube: It’s absolutely worth it!

  • 9 July 2020

    PDFs of 1st Patient Event Presentations available for download

    The PDFs of the 3 presentations by Profs. Jonel Trebica, Aleksander Krag, and Minneke Coenraad are now freely accessible on the DOWNLOADS page. Alternatively, just click on the respective screenshot below to view the desired presentation in your browser.

  • 16 June 2020

    SAVE THE DATE – First online patient event on 8 July 2020!

    We kindly invite you to the first online patient event of the MICROB-PREDICT project: On Wednesday, 8 July 2020, from 10:30-11:30 AM, we would like to inform you and other cirrhosis patients on our project and its implications for the future management of patients with cirrhosis and discuss with you how to best disseminate this information in the national patient associations. We look forward to meeting you virtually at July 8th!

  • 28 May 2020

    New ACLF review article in the New England Journal of Medicine!

    Three clinical experts on ACLF just published a joint review article on “Acute-on-Chronic Liver Failure”. Thanks to Vicente Arroyo, Richard Moreau, and Rajiv Jalan for this excellent review and for highlighting the importance of increased clinical research and efforts to prevent decompensated cirrhosis and ACLF. The article was published today in the New England Journal of Medicine (volume 382(22): pages 2137-2145; doi: 10.1056/NEJMra1914900)

  • 26 May 2020

    Video of the 1st MICROB-PREDICT Masterclass on „ Acute-on-Chronic Liver Failure (ACLF)” by Prof. Dr. Jonel Trebicka

    Prof. Dr. Jonel Trebicka, project coordinator on behalf of EFCLIF and Professor for translational hepatology at the Department of Internal Medicine I, University Clinic Frankfurt speaks about current status and recent advances of ACLF research. The talk was recorded on 20 January 2020 at the occasion of the first MICROB-PREDICT MasterClass in Frankfurt.

  • 1 April 2020

    Model describing typical treatment paths in decompensated cirrhosis

    Prof. Hans Olav Melberg from UiO concludes an important step and releases a report about typical treatment paths in decompensated cirrhosis, information about the probability of going from one state to another, as well as the costs and quality of life in patients in each state.

    More information

    Download report (PDF | 1 MB)

  • 1 April 2020

    Important ethics deliverables published

    Prof. Itziar de Lecuona, leader of the ethics WP, and colleagues publish three important ethics deliverables of MICROB-PREDICT: Informed consent templates for use of human biological samples and personal data in biomedical research, Public engagement strategy to design MICROB-PREDICT along with the need of patients and Codes of conduct applicable and research integrity policy including publications in journals.

    More information

  • 22 January 2020

    Successful 2nd General Assembly Meeting in Königstein

    From 20th-22nd January 2020, 71 delegates of the MICROB-PREDICT consortium met in Königstein near Frankfurt a.M., Germany, to discuss the progress and results after the end of the first year of the project. We are happy to conclude that the project is in schedule and the first results come in nicely.

  • 20 January 2020

    First master class for Early Career Scientists

    On 20th January 2020, 48 participants of the MICROB-PREDICT Consortium, of which 24 Early Career Scientists attended the first master class which was organized as part of the WP9 training programme before the start of the 2nd General Assembly Meeting, in the hospital of the Goethe University Frankfurt, Germany. Talks included “How to write a successful grant application” (Ameli Schwalber and Jonel Trebicka), “ACLF: current status and recent advances” (Jonel Trebicka) and “Microbiome: current standards and challenges” (Peer Bork). Overall, the feedback was positive, and this format will be repeated again at future General Assembly meetings.

  • 6 November 2019

    Big data and artificial intelligence (AI)

    Big data and artificial intelligence (AI) are not the future, they are the present. Our ethics WP Leader Prof. Itziar de Lecuona speaks about “Big Data and Artificial Intelligence: Opportunities for Clinical Decision-Making and Health Care Assessment”.

    More information

  • 17 October 2019

    Policy for integrating the six agendas of responsible research and innovation

    Read our policy on how we implement responsible research and innovation of our six agendas (ethics, gender equality, public engagement, governance, scientific education and open access) in MICROB-PREDICT. Our legal and ethics team explains measures to take into account regarding governance, ethics, gender equality, public engagement, open access and scientific education. Download the policy here.

  • 6 September 2019

    All PREDICT samples have been shipped to our specialty labs

    All PREDICT samples have been shipped to our specialty labs. The majority of proteomics and metabolomics measurements are complete. Congratulations WP3!

  • 2 July 2019

    First important milestones achieved

    MICROB-PREDICT partners received ethics approvals for shipment of samples. More than 700 samples have been aliquoted and were shipped to specialty labs. Now, data generation begins.

  • 30 June 2019

    MICROB-PREDICT Informed consent policy

    The MICROB-PREDICT policy for human subjects, samples and data describes the ethical and legal framework for the planned research interventions, the implications for research participants and obligations for those conducting research. Download the policy here.

  • 12 April 2019


    Jonel Trebicka and Minneke Coenraad presented the project’s objectives, its consortium members, and the expected impact of MICROB-PREDICT at the International Liver Congress (ILC) in Vienna, Austria. The annual congress is organised by EASL.

  • 26 March 2019

    First internal meeting on specifics of biosensor development

    The first meeting of work package 5 (WP5) members dedicated to validation of biomarkers and biosensor development was held at the Catalan Institute of Nanoscience and Nanotechnology (ICN2) in Barcelona. The aim was to initiate collaboration of ICN2 and the French Alternative Energies and Atomic Energy Commission (CEA) for the development of point-of-care (POC) diagnostic tests.

  • 31 January 2019

    1st press conference in Barcelona

    Following the project’s Kick-Off Meeting, EF-CLIF organised a well-attended press conference for local journalists in Barcelona that resulted in a widespread press coverage during the next days across Spain and Europe!

  • 1 January 2019

    MICROB-PREDICT kicks off!

    Today, the 6-year long, pan-European research project begins. All of us are excited to roll up our sleeves and get to work!