Focus on human microbiome to fight liver cirrhosis
22 European institutions join forces in MICROB-PREDICT to improve the prevention and treatment of chronic liver disease (cirrhosis). We aim to identify microbiome-based biomarkers and mechanisms that predict in advance when the body can no longer compensate for the dysfunctional liver (decompensated cirrhosis), when such decompensated cirrhosis will progress to acute-on-chronic liver failure (ACLF), and a patient’s individual treatment response. Based on such biomarkers, we strive to develop novel diagnostic tools for earlier and better patient stratification and to establish personalised and effective treatment strategies.
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Privacy PolicyJoin the MICROB-PREDICT Consensus Conference at EASL Congress
We cordially invite hepatology & microbiome colleagues who attend EASL Congress 2026 in Barcelona to join the MICROB-PREDICT Consensus Conference on Wednesday, 27 May (15:30 – 18:30 h, Jansen Room). Chaired by Prof Jonel Trebicka and Prof Minneke Coenraad, the session brings together leading researchers to discuss microbiome-based mechanisms and biomarkers for improved patient stratification and therapeutic response prediction in decompensated cirrhosis and ACLF. The Consensus Conference Programme combines expert presentations and structured discussions to identify key findings, knowledge gaps, and future research priorities in this rapidly evolving field. The meeting is face-to-face (not hybrid), and participants need to be registered for EASL Congress to attend the Consensus Conference. We look forward to seeing you there!
More newsNew video: Albumin reduces inflammation & protects against multi-organ injury
In this YouTube Video, Alexandra Phillips, a PhD candidate in the group of Rajiv Jalan at University College London (UCL), United Kingdom, presents her pre-clinical and translational research in animal models of liver failure and ACLF, particularly how albumin infusions reduce endotoxin sensitivity by modulating TLR4-related inflammation, and how albumin protects against multi-organ injury in these animals. Research in these animal models is absolutely crucial to identify biological targets and to develop much-needed treatment options for humans suffering from advanced cirrhosis or ACLF, many of whom - unfortunately - still die if they do not receive a liver transplant because there are still no effective treatments available.
More newsMICROB-PREDICT project video
Focus on human microbiome to fight liver cirrhosis: 22 European institutions joined forces in January 2019 to improve the prevention and treatment of chronic liver disease (cirrhosis) within the MICROB-PREDICT project. We aim to identify microbiome-based biomarkers and mechanisms that predict in advance when the body can no longer compensate for the dysfunctional liver (decompensated cirrhosis) and decompensated cirrhosis progresses to acute-on-chronic liver failure (ACLF), and individual treatment responses of patients. Coordinator Jonel Trebicka gives a brief overview of the project in this video.
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