For Scientists

Publications

View topic-related background literature as well as publications of the MICROB-PREDICT consortium itself. To receive our newsletter, please subscribe here!

MICROB-PREDICT Publications

2025

• Kerbert AJC, Engelmann C, Habtesion A, et al. (2025)
  ‍Hyperammonemia induces programmed liver cell death
  Sci Adv, eISSN 2375-2548
• Nishijima S,Stankevic E, Aasmets O, (2025)
  ‍Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations
  Cell, Volume 188, Issue 1, pp. 222-236.e15
• Rosenberger FA, Mädler SC, Holtz Thorhauge K, et al. (2025)
  ‍Deep Visual Proteomics maps proteotoxicity in a genetic liver disease
  Nature, Preprint
• Schulz M, Angeli P, Trebicka J (2025)
  ‍Acute and non-acute decompensation of liver cirrhosis (47/130)
  Liver International, Volume 45, Issue 3, pp. 1 - 14
• Sturm L, Schultheiss M, Stöhr F, et al. (2025)
  ‍The Freiburg Index of Post-TIPS Survival (FIPS) identifies patients at risk for further decompensation and ACLF after TIPS
  Journal of Hepatology, S0168 - 8278
• Thiele M, Johansen S, Israelsen M, et al. (2025)
  ‍Noninvasive assessment of hepatic decompensation
  Hepatology, Volume 81, Issue 3
• Trebicka J, Aguilar F, Farias AQ, et al. (2025)
  ‍Gene score to quantify systemic inflammation in patients with acutely decompensated cirrhosis
  Gut, eISSN 1468-3288
• Trebicka J, Garcia-Tsao G (2025)
  ‍Controversies regarding albumin therapy in cirrhosis
  Hepatology, Volume 81, Issue 1, pp. 288-303

2024

• Bartimoccia S, Praktiknjo M, Nocella C, et al. (2024)
  ‍Association between endotoxemia and blood no in the portal circulation of cirrhotic patients: results of a pilot study
  Intern Emerg Med, Volume 19, Issue 3, pp. 713-720
• Brol MJ, Canbay A, Trebicka J (2024)
  ‍Alcohol-associated hepatitis: a neutrophile disease?
  Gut, Volume 74, Issue 1
• Brol MJ, Drebber U, Yu X, et al. (2024)
  ‍Stage of fibrosis is not a predictive determinant of weight loss in patients undergoing bariatric surgery
  Surg Obes Relat Dis, Volume 20, Issue 8, pp. 759-766
• Clària J, Aguilar F, Lozano JJ, et al. (2024)
  ‍Albumin reprograms the B cell transcriptional landscape and improves neutrophil antimicrobial function in patients with decompensated cirrhosis
  JHEP Reports, Volume 6, Issue 11
• Feio-Azevedo, Rita; Boesch, Markus; Radenkovic, Silvia; || Feio-Azevedo R, Boesch M, Radenkovic S, et al. (2024)
  ‍Distinct immunometabolic signatures in circulating immune cells define disease outcome in acute-on-chronic liver failure
  Hepatol Commun, Volume 81, Issue 2, pp. 509-522
• Gilda Carota A, Bonini A, Urban M, et al. (2024)
  ‍Low-cost inkjet-printed nanostructured biosensor based on CRISPR/Cas12a system for pathogen detection
  Biosensors and Bioelectronics, Volume 258, ISSN 0956-5663
• Hu L, Rossetti M, Bergua JF, et al. (2024)
  ‍Harnessing Bioluminescent Bacteria to Develop an Enzymatic-free Enzyme-linked immunosorbent assay for the Detection of Clinically Relevant Biomarkers
  ACS Applied Materials & Interfaces, Volume 16, Issue 24
• Juanola A, Ma AT, de Wit K, et al. (2024)
  ‍Novel prognostic biomarkers in decompensated cirrhosis: a systematic review and meta-analysis
  Gut, Volume 73, Issue 1
• Keshoofi P, Schindler P, Rennebaum F, et al. (2024)
  ‍Imaging-based diagnosis of sarcopenia for transplant-free survival in primary sclerosing cholangitis
  BMC Gastroenterol, Volume 24, Issue 1, 145
• Kraus N, Uschner FE, Moeslein M, et al. (2024)
  ‍Decompensated MASH-Cirrhosis Model by Acute and Toxic Effects of Phenobarbital
  Cells, Volume 13, Issue 20 (1707)
• Laleman W, Peiffer KH, Tischendorf M, et al. (2024)
  ‍Role of endoscopy in hepatology
  Dig Liver Dis, Volume 56, Issue 7, pp. 1185-1195
• Laleman W, Vanderschueren E, Mehdi ZS, et al. (2024)
  ‍Endoscopic procedures in hepatology: Current trends and new developments
  J Hepatol, Volume 80, Issue1, pp. 124-139
• Mücke MM, El Bali N, Schwarzkopf KM, et al. (2024)
  ‍The Role of Hypoxia-Inducible Factor 1 Alpha in Acute-on-Chronic Liver Failure
  Int J Mol Sci, Volume 25, Issue 3, 1542
• Mücke MM, Hernández-Tejero M, Gu W, et al. (2024)
  ‍Terlipressin therapy is associated with increased risk of colonisation with multidrug-resistant bacteria in patients with decompensated cirrhosis
  Aliment Pharmacol Ther, Volume 59, Issue 7, pp. 877-888
• Palomino-Echeverria S, Huergo E, Ortega-Legarreta A, et al. (2024)
  ‍A robust clustering strategy for stratification unveils unique patient subgroups in acutely decompensated cirrhosis
  J Tranl Med, Volume 22, Issue 1, 599
• Praktiknjo M, Trebicka J (2024)
  ‍Operating under pressure: Is there a place for preoperative TIPS?
  JHEP Rep, Volume 6, Issue 4, 101034
• Rosenberger F, Thorhauge K, Mädler S, et al. (2024)
  ‍OS-041-YI A spatiotemporal map of the hepatocyte proteome in alpha-1 antitrypsin deficiency by single-cell and visual proteomics
  Journal of Hepatology, Volume 80, S32
• Rosenberger F, Treit P, Albrecht V, et al. (2024)
  ‍Plasma proteomics uncovers progression markers of acute-on-chronic liver failure
  Journal of Hepatology, Volume 89, S193
• Thiele M, Villesen IF, Niu L, et al. (2024)
  ‍Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases
  J Hepatol, Volume 81, Issue 2, pp. 345-359
• Thorhauge K, Semmler G, Johansen S, et al. (2024)
  ‍Using liver stiffness to predict and monitor the risk of decompensation and mortality in patients with alcohol-related liver disease
  Journal of Hepatology, Volume 81, Issue 1, pp. 23-32
• Torp N, Israelsen M, Coenraad M, et al. (2024)
  ‍Personalised human albumin in patients with cirrhosis and ascites: design and rationale for the ALB-TRIAL – a randomised clinical biomarker validation trial
  BMJ Open, Volume 14, Issue 2, e079309
• Trebicka J, Hernaez R, Shawcross DL, Gerbes AL (2024)
  ‍Recent advances in the prevention and treatment of decompensated cirrhosis and acute-on-chronic liver failure (ACLF) and the role of biomarkers
  Gut, Volume 73, Issue 6, pp. 1015-1024
• Wei Zhang I, Sánchez-Rodríguez MB, López-Vicario C, et al. (2024)
  ‍Palmitoylcarnitine impairs immunity in decompensated cirrhosis
  JHEP Reports, Volume 6, Issue 11, eCollection

2023

• Bachtler N, Torres S, Ortiz C, et al. (2023)
  ‍The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells
  PLoS One, Volume 18, Issue 1 (e0270288)
• Buch S, Innes H, Lutz PL, et al. (2023)
  ‍Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study
  Gut BMJ, Volume 72, Issue 2, pp. 381-391
• Clària J, Arroyo V, Moreau R (2023)
  ‍Roles of systemic inflammatory and metabolic responses in the pathophysiology of acute-on-chronic liver failure
  JHEP Reports, Volume 5, Issue 9 (100807)
• de Lecuona I (2023)
  ‍Ethical and legal analysis of the international regulation on biomedical research
  ISBN: 978-84-1125-900-2
• Dold L, Nielsen MJ, Praktiknjo M, et al. (2023)
  ‍Circulating levels of endotrophin and cross-linked type III collagen reflect liver fibrosis in people with HIV
  BMC infectious diseases, Volume 23, Issue 1 (52)
• Duran Güell M (2023)
  ‍Effects of human serum albumin on TNFα-induced cell death and mitochondrial dysfunction in the liver cells
  Dissertation
• Duran-Güell M, Garrabou G, Flores-Costa R, Casulleras M, et al. (2023)
  ‍Essential role for albumin in preserving liver cells from TNFα-induced mitochondrial injury
  Faseb Journal, Volume 37, Issue 3 (e22817)
• Engelmann C, Zhang I W, Clària J (2023)
  ‍Mechanisms of immunity in acutely decompensated cirrhosis and acute-on-chronic liver failure
  Liver International, Online Version
• Gu W, de Lédinghen V, Aubé C, et al. (2023)
  ‍Hepatocellular Cancer Surveillance in Patients with Advanced Chronic Liver Disease
  NEJM Evid, Volume 3, Issue 11
• Gu W, Kimmann M, Laleman W, Praktiknjo M, Trebicka J (2023)
  ‍To TIPS or Not to TIPS in High Risk of Variceal Rebleeding and Acute-on-Chronic Liver Failure
  Seminars in Liver Disease, Volume 43, Issue 2, pp. 189-205.
• Gu W, Schaaf L, Hortlik H, et al. (2023)
  ‍Epidemiology of liver transplantation and post-LT complications in Germany: nationwide study (2005-2018)
  European Journal of Gastroenterology & Hepatology, Volume 35, Issue 11, pp. 1289-1297
• Gu W, Zeleke Y, Hortlik H et al. (2023)
  ‍Use and outcome of TIPS in hospitalized patients in Germany: A Nationwide study (2007-2018)
  Hepatology communications, Voulme 7, Issue10 (e0237)
• Kimmann M, Trebicka J (2023)
  ‍Acute-On-Chronic Liver Failure: Current Interventional Treatment Options and Future Challenges
  Journal of personalized medicine, Volume 13, Issue 7 (1052)
• Kronborg TM, Schierwagen R, Trošt K, et al. (2023)
  ‍Atorvastatin for patients with cirrhosis. A randomized, placebo-controlled trial
  Hepatol Commun, Volume 7, Issue 12, e0332
• López‐Vicario C, Sebastián D, Casulleras M, Duran‐Güell M et al. (2023)
  ‍Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease
  Hepatology, Volume 77, Issue 4, pp. 1303-1318
• Mehta G, Riva A, Ballester MP, et al. (2023)
  ‍Serological response and breakthrough infection after COVID-19 vaccination in patients with cirrhosis and post-liver transplant
  Hepatol Commun, ISSN 2471-254X
• Ortiz C, Klein S, Reul WH, et al. (2023)
  ‍Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1
  Cell Reports, Volume 42, Issue 2 (112059)
• Reiniš J, Petrenko O, Simbrunner B, et al. (2023)
  ‍Assessment of portal hypertension severity using machine learning models in patients with compensated cirrhosis
  Journal of Hepatology, Volume 78, Issue 2, pp. 390-400
• Ruiz-Margáin A, Pohlmann A, Lanzerath S, et al. (2023)
  ‍Myostatin is associated with the presence and development of acute-on-chronic liver failure
  JHEP Reports, Volume 5, Issue 8 (100761)
• Sauerbruch T, Hennenberg M, Trebicka J, Schierwagen R (2023)
  ‍Beta-blockers in patients with liver cirrhosis: Pragmatism or perfection?
  Frontiers in Medicine (Lausanne), Volume 9 (1100966)
• Schierwagen R, Gu W, Brieger A, et al. (2023)
  ‍Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure
  American journal of physiology. Cell physiology, Volume 325, Issue 1, pp. 129-140
• Thielert M, Weiss C AM, Mann M, Rosenberger F (2023)
  ‍Spatial Proteomics of Single Hepatocytes with Multiplexed Data-Independent Acquisition (mDIA)
  Methods in Molecular Biology/Mass Spectrometry Based Single Cell Proteomics, Volume 2817, pp. 97-113
• Torres S, Ortiz C, Bachtler N, Gu W et al. (2023)
  ‍Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
  Hepatology, Volume 77, Issue 4, pp. 1228-1240
• Tyc O, Shi Y, Fan YC, Trebicka J, Xiang X (2023)
  ‍Editorial: Acute-on-chronic liver failure: systemic inflammation and immunosuppression
  Frontiers in Immunology, Volume 14 (1260749)
• Weiss E, de la Peña-Ramirez C, Aguilar F, et al. (2023)
  ‍Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)
  Gut BMJ, Volume 72, Issue 8, pp. 1581-1591

2022

• Castelli FA, Rosati G, Moguet C, Fuentes C, et al. (2022)
  ‍Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests
  Analytical and Bioanalytical Chemistry, Volume 414, Issue 2, pp. 759-789
• Chang J, Höfer P, Böhling N, et al. (2022)
  ‍Preoperative TIPS prevents the development of postoperative acute-on-chronic liver failure in patients with high CLIF-C AD score
  JHEP Reports, Volume 4, Issue 3 (100442)
• Faron A, Abu-Omar J, Chang J, et al. (2022)
  ‍Combination of Fat-Free Muscle Index and Total Spontaneous Portosystemic Shunt Area Identifies High-Risk Cirrhosis Patients
  Frontiers in Medicine (Lausanne), Volume 9 (831005)
• Gu W, Hortlik H, Erasmus HP, et al. (2022)
  ‍Trends and the course of liver cirrhosis and its complications in Germany: Nationwide population-based study (2005 to 2018)
  The Lancet Regional Health - Europe, Volume 12 (100240)
• Herath CB, Angus PW, Trebicka J (2022)
  ‍Editorial: Portal Hypertension in Cirrhosis: From Pathogenesis to Novel Treatments
  Frontiers in Physiology, Volume 13 (864083)
• Innes H, Nischalke HD, Guha IN, et al. (2022)
  ‍The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis
  Hepatology Communications, Volume 6, Issue 5, pp. 1213-1226
• Menghao L, Kai L, Shihao T, Yong L, Jonel T et al. (2022)
  ‍Restoration of the gut microbiota is associated with a decreased risk of hepatic encephalopathy after TIPS
  JHEP Reports, Volume 4, Issue 5 (100448)
• Niu L, Geyer PE, Gupta R, et al. (2022)
  ‍Dynamic human liver proteome atlas reveals functional insights into disease pathways
  Molecular Systems Biology, Volume 18, Issue 5 (e10947)
• Prado V, Hernández-Tejero M, Mücke MM, et al. (2022)
  ‍Rectal colonization by resistant bacteria increases the risk of infection by the colonizing strain in critically ill patients with cirrhosis
  Journal of Hepatology, Volume 76, Issue 5, pp. 1079–1089.
• Sánchez-Rodríguez MB, Téllez É, Casulleras M, Borràs FE, et al. (2022)
  ‍Reduced Plasma Extracellular Vesicle CD5L Content in Patients With Acute-On-Chronic Liver Failure: Interplay With Specialized Pro-Resolving Lipid Mediators
  Frontiers in Immunology, Volume 13 (842996)
• Schulz MS, Gu W, Schnitzbauer AA, Trebicka J (2022)
  ‍Liver Transplantation as a Cornerstone Treatment for Acute-On-Chronic Liver Failure
  Transpl International, Volume 35 (10108)
• Tantai X, Liu Y, Yeo YH, Praktiknjo M, Trebicka J, et al. (2022)
  ‍Effect of sarcopenia on survival in patients with cirrhosis: A meta-analysis
  Journal of Hepatology, Volume 76, Issue 3, pp. 588-599
• Trebicka J, Gu W, de Ledinghen V, Aubé C, et al. (2022)
  ‍Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease
  GUT, Volume 71, Issue 2, pp. 402-414
• Yu X, Elfimova N, Müller M, et al. (2022)
  ‍Autophagy-Related Activation of Hepatic Stellate Cells Reduces Cellular miR-29a by Promoting Its Vesicular Secretion
  CMGH, Volume 13, Issue 6, pp. 1701-1716
• Zhang I W, Curto A, López-Vicario C, Casulleras M, Duran-Güell M, et al. (2022)
  ‍Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure
  Journal of Hepatology, Volume 76, Issue 1, pp. 93-106

2021

• Abraldes JG, Albillos A, Baiges A, Bajaj J, et al. (2021)
  ‍Baveno VII – Renewing consensus in portal hypertension
  Journal of Hepatology, Volume 76, Issue 4, pp. 959-974
• Bischoff J, Gu W, Trebicka J, et al. (2021)
  ‍Stratifying the risk of NAFLD in patients with HIV under combination antiretroviral therapy (cART)
  EClinicalMedicine, Volume 40 (101116)
• Blaya D, Pose E, Coll M, Caballería J, Trebicka J, et al. (2021)
  ‍Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure
  JHEP Reports, Volume3, Issue 2 (100233)
• Castelli FA, Rosati G, Moguet C, et al. (2021)
  ‍Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests
  Anal Bioanal Chem: 1-31. Online ahead of print
• Chang J, Bamarni A, Böhling N, Trebicka J, et al. (2021)
  ‍Elective Surgery but not Transjugular Intrahepatic Portosystemic Shunt Precipitates Acute-On-Chronic Liver Failure
  Hepatology Communications, Volume 5, Issue 7, pp. 1265-1277
• Chang J, Meinke J, Wehner S, Trebicka J, et al. (2021)
  ‍Extrahepatic Surgery in Cirrhosis Significantly Increases Portal Pressure in Preclinical Animal Models
  Frontiers in Physiology, Volume 12, pp. 720-898
• Clària J, Curto A, Moreau R, Colsch B, López-Vicario C, Trebicka J, et al. (2021)
  ‍Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis
  Journal of Hepatology, Volume 75, Issue 5, pp. 1116-1127
• Diehl V, Huber LS, Trebicka J, Wygrecka M, Iozzo RV, Schaefer L (2021)
  ‍The Role of Decorin and Biglycan Signaling in Tumorigenesis
  Frontiers in Oncology, Volume 11
• Engelmann C, Herber A, Franke A, Bruns T, et al. (2021)
  ‍Granulocyte-colony stimulating factor (G-CSF) to treat acute-on-chronic liver failure: A multicenter randomized trial (GRAFT study)
  Journal of Hepatology, Volume 75, Issue 6, pp. 1346-1354
• Ferstl P, Trebicka J (2021)
  ‍Acute Decompensation and Acute-on-Chronic Liver Failure
  Clinics in Liver Disease, Volume 25, Issue 2, pp. 419-430
• Fuentes-Chust C, Parolo C, Rosati G, Rivas L, et al. (2021)
  ‍The Microbiome Meets Nanotechnology: Opportunities and Challenges in Developing New Diagnostic Devices
  Advanced Materials, Volume 33, Issue 18 (2006104)
• Geyer PE, Mann SP, Treit PV, Mann M. (2021)
  ‍Plasma Proteomes Can Be Reidentifiable and Potentially Contain Personally Sensitive and Incidental Findings
  Molecula & Cellular Proteomics, Volume 20 (10035)
• Innes H, Nischalke HD, Guha IN, Weiss KH, et al. (2021)
  ‍The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis
  Hepatology Communications, Volume 6, Issue 5, pp. 1213-1226
• Iwakiri Y, Trebicka J (2021)
  ‍Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy
  JHEP Reports, Volume 3, Issue 4 (100316)
• Lin T, Wang S, Munker S, Jung K, Macías-Rodríguez RU, Trebicka J, et al. (2021)
  ‍Follistatin-controlled activin-HNF4α-coagulation factor axis in liver progenitor cells determines outcome of acute liver failure
  Hepatology, Volume 75, Issue 2, pp. 322-337
• Mann SP, Treit PV, Geyer PE, Omenn GS, Mann M (2021)
  ‍Ethical Principles, Constraints, and Opportunities in Clinical Proteomics
  MCP, Volume 20 (100046)
• Praktiknjo M, Abu-Omar J, Trebicka J, et al (2021)
  ‍Controlled underdilation using novel VIATORR® controlled expansion stents improves survival after transjugular intrahepatic portosystemic shunt implantation
  JHEP, Volume 3, Issue 3, 100264
• Queck A, Uschner FE, Ferstl PG, et al. (2021)
  ‍Role of circulating angiogenin levels in portal hypertension and TIPS
  PLoS One, Volume 16, Issue 8 (e0256473)
• Rosati G, Idili A, Parolo C, Fuentes-Chust C, et al. (2021)
  ‍Nanodiagnostics to Face SARS-CoV‑2 and Future Pandemics: From an Idea to the Market and Beyond
  ACS Nano, Volume 15, Issue 11, pp. 17137-17149
• Rosati G, Urban M, Zhao L, et al. (2021)
  ‍A plug, print & play inkjet printing and impedance-based biosensing technology operating through a smartphone for clinical diagnostics
  Biosensors and Bioelectronics, Volume 196, pp. 1-10
• Sauerbruch T, Hennenberg M, Trebicka J, Beuers U (2021)
  ‍Bile Acids, Liver Cirrhosis, and Extrahepatic Vascular Dysfunction
  Frontiers in Physiology, Volume 12, pp. 718-783
• Schulz M, Trebicka J (2021)
  ‍Acute-on-chronic liver failure: a global disease
  Gut BMJ, Volume 71, Issue 1, pp. 5-6
• Sturm L, Praktiknjo M, Bettinger D, Trebicka J, et al. (2021)
  ‍Prognostic Value of the CLIF-C AD Score in Patients With Implantation of Transjugular Intrahepatic Portosystemic Shunt
  Hepatology Communications, Volume 5, pp. 650-660
• Torres S, Brol MJ, Magdaleno F, Schierwagen R, Uschner FE, Klein S, Trebicka J, et al. (2021)
  ‍The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis
  Frontiers in Molecular Biosciences, Volume 8 (715765)
• Tranah TH, Edwards LA, Schnabl B, et al. (2021)
  ‍Targeting the gut-liver-immune axis to treat cirrhosis
  Gut, Volume 70, Issue 5, pp. 982-994
• Trebicka J, Bork P, Krag A, Arumugam M (2021)
  ‍Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure
  Nature Reviews Gastroenterology & Hepatology, Volume 18, Issue 3, pp. 167-180
• Trebicka J, MacNaughtan J, Schnabl B, Shawcross DL, Bajaj JS (2021)
  ‍The microbiota in cirrhosis and its role in hepatic decompensation
  Journal of Hepatology, Volume 75, Suppl. 1, pp. 67-81
• Zhang S, Suen S, Gong CL, Pham J, Trebicka J, et al. (2021)
  ‍Early transplantation maximizes survival in severe acute-on-chronic liver failure: Results of a Markov decision process model
  JHEP Reports, Volume 3, Issue 6, pp. 100

2020

• Bader JM, Geyer PE, Müller JB, et al. (2020)
  ‍Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer’s disease
  Molecular Systems Biology, Volume 16, Issue 6 (e9356)
• Benz F, Bogen A, Praktiknjo M, et al. (2020)
  ‍Serum levels of bone sialoprotein correlate with portal pressure in patients with liver cirrhosis
  PLoS One, Volume 15, Number 4 (e0231701)
• Cremonese C, Schierwagen R, Uschner FE, et al. (2020)
  ‍Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats
  Int J Mol Sci, Volume 21, Number 9, (3308)
• Cullaro G, Sharma R, Trebicka J, et al. (2020)
  ‍Precipitants of Acute-on-Chronic Liver Failure: An Opportunity for Preventative Measures to Improve Outcomes
  Liver Transplantation, Volume 26, Issue 2, pp. 283-293
• García-Pagán JC, Bosch J, Trebicka J, et al. (2020)
  ‍Letter: improve survival! Place early pre-emptive TIPSS in high-risk variceal bleeders
  Alimentary pharmacology & therapeutics, Volume 52, Issue 5, pp. 927-928.
• Itziar de Lecuona Ramírez (2020)
  ‍Pautes per avaluar projectes de recerca i innovació en salut que utilitzin tecnologies emergents i dades personals
  Published by: Edicions de la Universitat de Barcelona
• López-Vicario C, Checa A, Urdangarin A, et al. (2020)
  ‍Targeted lipidomics reveals extensive changes in circulating lipid mediators in patients with acutely decompensated cirrhosis
  Journal of Hepatology, Volume 73, Issue 4, pp. 817-828
• Monteiro S, Grandt J, Uschner FE, et al. (2020)
  ‍Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation
  Gut, Volume 70, Issue 2, pp. 379-387
• Müller JB, Geyer PE, Colaço AR, et al. (2020)
  ‍The proteome landscape of the kingdoms of life
  Nature, Volume 582, pp. 592–596
• Praktiknjo M, Simón-Talero M, Römer J, et al. (2020)
  ‍Total area of spontaneous portosystemic shunts independently predicts hepatic encephalopathy and mortality in liver cirrhosis
  Journal of Hepatology, Volume 72, Issue 6, pp. 1140-1150
• Queck A, Bode H, Uschner FE, et al. (2020)
  ‍Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis
  Frontiers in Immunology, Volume 11 (354)
• Rheinwalt KP, Drebber U, Schierwagen R, Klein SD, et al. (2020)
  ‍Baseline Presence of NAFLD Predicts Weight Loss after Gastric Bypass Surgery for Morbid Obesity
  Journal of Clinical Medicine, Volume 9, Issue 11, pp. 3430
• Schierwagen R, Dietrich P, Sauerbruch T, Trebicka J, et al. (2020)
  ‍β-Arrestin2 is increased in liver fibrosis in humans and rodents
  PNAS, Volume 117, No. 44, pp. 27082-27084
• Schierwagen R, Uschner FE, Ortiz C, et al. (2020)
  ‍The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease
  Frontiers in Immunology, Volume 11 (1352)
• Torres S, Abdullah Z, Brol MJ, et al. (2020)
  ‍Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview
  International Journal of Molecular Sciences, Volume 21, No. 6 (2027)
• Trebicka J, Sundaram V, Moreau R, et al. (2020)
  ‍Liver Transplantation for Acute-on-Chronic Liver Failure: Science or Fiction?
  Liver Transplantation, Volume 26, Issue 7, pp. 906-915
• Tyc O, Jansen C, Schierwagen R, et al. (2020)
  ‍Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease
  Liver Transplantation, Volume 26, Issue 12, pp. 1652-1657
• Van Rossum T, Ferretti P, Maistrenko OM, et al. (2020)
  ‍Diversity within species: interpreting strains in microbiomes
  Nature Reviews Microbiology, Volume 18, pp. 491–506
• Zeng-Brouwers J, Pandey S, Trebicka J, et al. (2020)
  ‍Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases
  Journal of Histochemistry & Cytochemistry, Volume 68, Issue 12, pp. 887-906

2019

• Coenraad M, Papp M, Trebicka J et al. (2019)
  ‍MICROB-PREDICT – 15 millió eurós költségvetéssel induló mikrobiom kutatási vizsgálat az Európai Unióban
  Central European Journal of Gastroenterology and Hepatology. -5 : 2 (2019), p. 40-42. -CEU-JGH. - 2415-9107
• Casey S, Schierwagen R, Mak KY, et al. (2019)
  ‍Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation
  Journal of Clinical Medicine, Volume 8, Issue 4, p 419
• Klein LM, Chang J, Gu W, et al. (2019)
  ‍The Development and Outcome of Acute-on-Chronic Liver Failure After Surgical Interventions
  Liver Transplantation, Volume 26, Issue 2, pp. 227-237
• Korenjak M, Všetičkova V, Credi B. (2019)
  ‍ELPA and EU medical research project brochure
  Booklet. Relevant pages: 20-23.
• Praktiknjo M, Clees C, Pigliacelli A, et al. (2019)
  ‍Sarcopenia Is Associated With Development of Acute-on-Chronic Liver Failure in Decompensated Liver Cirrhosis Receiving Transjugular Intrahepatic Portosystemic Shunt
  Clinical and translational gastroenterology, Volume 10, Issue 4 (e00025)
• Queck A, Carnevale R, Uschner FE, et al. (2019)
  ‍Role of portal venous platelet activation in patients with decompensated cirrhosis and TIPS
  Gut, Volume 69, pp. 1535–1536
• Queck A, Thomas D, Jansen C, et al. (2019)
  ‍Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis
  PLoS One, Volume 14, Issue 10 (e0222840)
• Schierwagen R, Alvarez-Silva C, Servant F, et al. (2019)
  ‍Trust is good, control is better: technical considerations in blood microbiome analysis
  Gut, Volume 69, Issue 7, pp. 1362-1363
• Torner M, Mangal A, Scharnagl H, et al. (2019)
  ‍Sex specificity of kidney markers to assess prognosis in cirrhotic patients with TIPS
  Liver International, Volume 40, Issue 1, pp. 186-193

Background Literature

2020

• Trebicka J, Fernandez J, Papp M, et al. (2020)
  ‍PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis
  Journal of Hepatology, Volume 74, Issue 5, pp. 1097-1108
• Trebicka J, Fernandez J, Papp M, et al. (2020)
  ‍The PREDICT study uncovers three clinical courses in acutely decompensated cirrhosis with distinct pathophysiology
  Journal of Hepatology, Volume 73, Issue 4, pp. 842 - 854

2019

• Alvarez-Silva C, Schierwagen R, Pohlmann A, et al. (2019)
  ‍Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis
  Frontiers in Immunology, Volume 10, Article number 69
• Clària J, Moreau R, Fenaille F, et al. (2019)
  ‍Orchestration of Tryptophan-Kynurenine Pathway, Acute Decompensation, and Acute-on-Chronic Liver Failure in Cirrhosis
  Hepatology, Volume 69, Issue 4, pp. 1686-1701
• Fernández J, Prado V, Trebicka J, et al. (2019)
  ‍Multidrug-resistant bacterial infections in patients with decompensated cirrhosis and with acute-on-chronic liver failure in Europe
  Journal of Hepatology, Volume 70, Issue 3, pp. 398-411
• Letunic I, Bork P (2019)
  ‍Interactive Tree Of Life (iTOL) v4: recent updates and new developments
  Nucleic Acids Research, Volume 47, Issue W1, pp. W256-W259
• Niu L, Geyer PE, Wewer Albrechtsen NJ, et al. (2019)
  ‍Plasma proteome profiling discrovers novel proteins associated with non-alcoholic fatty liver disease
  Molecular Systems Biology, Volume 15, Issue 3 (e8793)
• Quesada-González D, Sena-Torralba A, Wicaksono WP, et al. (2019)
  ‍Iridium oxide (IV) nanoparticle-based lateral flow immunoassay
  Biosensors and Bioelectronics, Volume 132, pp. 132-135
• Romanov N, Kuhn M, Aebersold R, et al. (2019)
  ‍Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals
  Cell, Volume 177, Issue 5, pp. 1308-1318
• Schmidt TS, Hayward MR, Coelho LP (2019)
  ‍Extensive transmission of microbes along the gastrointestinal tract
  Elife, Volume 8, Article number 42693
• Solà E, Solé C, Ginès P (2019)
  ‍New Strategies for the Management of Decompensated Cirrosis: Long-Term Albumin Administration for Everyone?
  Hepatology, Volume 69, Issue 5, pp. 2289-2291
• Trebicka J, Amoros A, Pitarch C, et al. (2019)
  ‍Addressing Profiles of Systemic Inflammation Across the Different Clinical Phenotypes of Acutely Decompensated Cirrhosis
  Frontiers in Immunology, Volume 10, Article number 476

2018

• Schierwagen R, Alvarez-Silva C, Madsen MSA, et al. (2018)
  ‍Circulating microbiome in blood of different circulatory compartments
  Gut, Volume 68, Issue 3, pp. 578-580
• Schmidt TSB, Raes J, Bork P (2018)
  ‍The human gut microbiome: From association to modulation
  Cell, Volume 172, Issue 6, pp. 1198-1215
• Trebicka J, Reiberger T, Laleman W (2018)
  ‍Gut-liver axis links portal hypertension to acute-on-chronic liver failure
  Visceral Medicine, Volume 34, Issue 4, pp. 270-275

2017

• Hackstein CP, Assmus LM, Welz M, et al. (2017)
  ‍Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis
  Gut, Volume 66, Issue 3, pp. 507-518

2016

• Arroyo V, Moreau R, Patrick S, et al. (2016)
  ‍Acute-on-chronic liver failure in cirrhosis
  Nature Reviews Disease Primers, Volume 2, Article number 16041
• Spinella R, Sawhney R, Jalan R (2016)
  ‍Albumin in chronic liver disease: structure, functions and therapeutic implications
  Hepatology International, Volume 10, Issue 1, pp. 124-132
• Tilg H, Cani PD, Mayer EA (2016)
  ‍Gut microbiome and liver diseases
  Gut, Volume 65, Issue 12, pp. 2035-2044

2014

• Qin N, Yang F, Li A, et al. (2014)
  ‍Alterations of the human gut microbiome in liver cirrhosis
  Nature, Volume 513, pp. 59-64

2013

• Moreau R, Jalan R, Gines P, et al. (2013)
  ‍Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis
  Gastroenterology, Volume 144, Issue 7, pp. 1426-1437