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Publications

View topic-related background literature as well as publications of the MICROB-PREDICT consortium itself. To receive our newsletter, please subscribe here!

MICROB-PREDICT Publications

• Castelli FA, Rosati G, Moguet C et al. (2021)
  ‍Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests
  Anal Bioanal Chem: 1-31. Online ahead of print.
• Tranah TH, Edwards LA, Schnabl B et al. (2021)
  ‍Targeting the gut-liver-immune axis to treat cirrhosis
  Gut. 70: 982-994.
• Trebicka J, Bork P, Krag A, Arumugam M. (2021)
  ‍Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure
  Nat Rev Gastroenterol Hepatol. 18: pp. 167–180.
• Bader JM, Geyer PE, Müller JB et al. (2020)
  ‍Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer’s disease
  Mol Syst Biol. 16: e9356
• Benz F, Bogen A, Praktiknjo M et al. (2020)
  ‍Serum levels of bone sialoprotein correlate with portal pressure in patients with liver cirrhosis
  PLoS One. 15(4): e0231701.
• Cremonese C, Schierwagen R, Uschner FE et al. (2020)
  ‍Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats
  Int J Mol Sci. 21(9): 3308.
• Cullaro G, Sharma R, Trebicka J et al. (2020)
  ‍Precipitants of Acute-on-Chronic Liver Failure: An Opportunity for Preventative Measures to Improve Outcomes
  Liver Transpl. 26(2): 283-293.
• García-Pagán JC, Bosch J, Trebicka J et al. (2020)
  ‍Letter: improve survival! Place early pre-emptive TIPSS in high-risk variceal bleeders
  Aliment Pharmacol Ther. 52(5): 927-928.
• López-Vicario C, Checa A, Urdangarin A et al. (2020)
  ‍Targeted lipidomics reveals extensive changes in circulating lipid mediators in patients with acutely decompensated cirrhosis
  J Hepatol. 73(4): 817-828.
• Monteiro S, Grandt J, Uschner FE et al. (2020)
  ‍Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation
  Gut. 70: 379-387.
• Müller JB, Geyer PE, Colaço AR et al. (2020)
  ‍The proteome landscape of the kingdoms of life
  Nature. 582: 592–596.
• Praktiknjo M, Simón-Talero M, Römer J et al. (2020)
  ‍Total area of spontaneous portosystemic shunts independently predicts hepatic encephalopathy and mortality in liver cirrhosis
  J Hepatol. 72(6): 1140-1150.
• Queck A, Bode H, Uschner FE et al. (2020)
  ‍Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis
  Front Immunol. 11: 354.
• Schierwagen R, Uschner FE, Ortiz C et al. (2020)
  ‍The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease
  Front Immunol. 11: 1352.
• Torres S, Abdullah Z, Brol MJ et al. (2020)
  ‍Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview
  Int J Mol Sci. 21(6): 2027.
• Trebicka J, Sundaram V, Moreau R et al. (2020)
  ‍Liver Transplantation for Acute-on-Chronic Liver Failure: Science or Fiction?
  Liver Transpl. 26(7): 906-915.
• Tyc O, Jansen C, Schierwagen R et al. (2020)
  ‍Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease
  Liver Transpl. 26: 1652-1657.
• Van Rossum T, Ferretti P, Maistrenko OM et al. (2020)
  ‍Diversity within species: interpreting strains in microbiomes
  Nat Rev Microbiol. 18: 491–506.
• Zeng-Brouwers J, Pandey S, Trebicka J et al. (2020)
  ‍Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases
  J Histochem Cytochem. 68(12): 887-906.
• Coenraad M, Papp M, Trebicka J et al. (2019)
  ‍MICROB-PREDICT – 15 millió eurós költségvetéssel induló mikrobiom kutatási vizsgálat az Európai Unióban
  Central European Journal of Gastroenterology and Hepatology. -5 : 2 (2019), p. 40-42. -CEU-JGH. - 2415-9107
• Casey S, Schierwagen R, Mak KY et al. (2019)
  ‍Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation
  J Clin Med. 8(4): 419.
• Klein LM, Chang J, Gu W et al. (2019)
  ‍The Development and Outcome of Acute-on-Chronic Liver Failure After Surgical Interventions
  Liver Transpl. 26(2): 227-237.
• Korenjak M, Všetičkova V, Credi B. (2019)
  ‍ELPA and EU medical research project brochure
  Booklet. Relevant pages: 20-23.
• Praktiknjo M, Clees C, Pigliacelli A et al. (2019)
  ‍Sarcopenia Is Associated With Development of Acute-on-Chronic Liver Failure in Decompensated Liver Cirrhosis Receiving Transjugular Intrahepatic Portosystemic Shunt
  Clin Transl Gastroenterol. 10(4): e00025.
• Queck A, Carnevale R, Uschner FE et al. (2019)
  ‍Role of portal venous platelet activation in patients with decompensated cirrhosis and TIPS
  Gut. 69: 1535–1536
• Queck A, Thomas D, Jansen C et al. (2019)
  ‍Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis
  PLoS One. 14(10): e0222840.
• Schierwagen R, Alvarez-Silva C, Servant F et al. (2019)
  ‍Trust is good, control is better: technical considerations in blood microbiome analysis
  Gut. 69(7): 1362-1363.
• Torner M, Mangal A, Scharnagl H et al. (2019)
  ‍Sex specificity of kidney markers to assess prognosis in cirrhotic patients with TIPS
  Liver Int. 40(1): 186-193.

Background Literature

• Trebicka J, Fernandez J, Papp M et al. (2020)
  ‍The PREDICT study uncovers three clinical courses in acutely decompensated cirrhosis with distinct pathophysiology.
  Journal of Hepatology, DOI: 10.1016/j.jhep.2020.06.013.
• Trebicka J, Fernandez J, Papp M et al. (2020)
  ‍PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis
  Journal of Hepatology. doi: 10.1016/j.jhep.2020.11.019.
• Alvarez-Silva C, Schierwagen R, Pohlmann A et al. (2019)
  ‍Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis.
  Front Immunol. 10: Article number 69.
• Clària J, Moreau R, Fenaille F et al. (2019)
  ‍Orchestration of Tryptophan-Kynurenine Pathway, Acute Decompensation, and Acute-on-Chronic Liver Failure in Cirrhosis.
  Hepatology. 69 (4):1686-1701.
• Fernández J, Prado V, Trebicka J et al. (2019)
  ‍Multidrug-resistant bacterial infections in patients with decompensated cirrhosis and with acute-on-chronic liver failure in Europe.
  J. Hepatol. 70 (3):398-411.
• Letunic I, Bork P (2019)
  ‍Interactive Tree Of Life (iTOL) v4: recent updates and new developments.
  Nucleic Acids Res. 47 (1):256-259.
• Niu L, Geyer PE, Wewer Albrechtsen NJ et al. (2019)
  ‍Plasma proteome profiling discrovers novel proteins associated with non-alcoholic fatty liver disease.
  Mol Syst Biol. 15: Article number 8793.
• Quesada-González D, Sena-Torralba A, Wicaksono WP et al. (2019)
  ‍Iridium oxide (IV) nanoparticle-based lateral flow immunoassay.
  Biosens Bioelectron. 132: 132-135.
• Romanov N, Kuhn M, Aebersold R et al. (2019)
  ‍Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals.
  Cell. 177 (5):1308-1318.
• Schmidt TS, Hayward MR, Coelho LP (2019)
  ‍Extensive transmission of microbes along the gastrointestinal tract.
  Elife. 8: Article number 42693.
• Solà E, Solé C, Ginès P (2019)
  ‍New Strategies for the Management of Decompensated Cirrosis: Long-Term Albumin Administration for Everyone?
  Hepatology. 69 (5):2289-2291.
• Trebicka J, Amoros A, Pitarch C et al. (2019)
  ‍Addressing Profiles of Systemic Inflammation Across the Different Clinical Phenotypes of Acutely Decompensated Cirrhosis.
  Front Immunol. 10: Article number 476.
• Schierwagen R, Alvarez-Silva C, Madsen MSA et al. (2018)
  ‍Circulating microbiome in blood of different circulatory compartments.
  Gut. In print
• Schmidt TSB, Raes J, Bork P (2018)
  ‍The human gut microbiome: From association to modulation.
  Cell. 172 (6):1198-1215.
• Trebicka J, Reiberger T, Laleman W (2018)
  ‍Gut-liver axis links portal hypertension to acute-on-chronic liver failure.
  Visc Med. 31 (4):270-275.
• Hackstein CP, Assmus LM, Welz M et al. (2017)
  ‍Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis.
  Gut. 66 (3): 507-518.
• Arroyo V, Moreau R, Patrick S et al. (2016)
  ‍Acute-on-chronic liver failure in cirrhosis
  Nature Reviews Disease Primers. 2: Article number 16041.
• Spinella R, Sawhney R and Jalan R (2016)
  ‍Albumin in chronic liver disease: structure, functions and therapeutic implications.
  Hepatol Int. 10 (1): 124-32.
• Tilg H, Cani PD, Mayer EA (2016)
  ‍Gut microbiome and liver diseases.
  Gut. 65 (12):2035-2044.
• Qin N, Yang F, Li A et al. (2014)
  ‍Alterations of the human gut microbiome in liver cirrhosis.
  Nature. 513 (7516):59-64.
• Moreau R, Jalan R, Gines P et al. (2013)
  ‍Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis.
  Gastroenterology. 144 (7):1426-1437.