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Publications
View topic-related background literature as well as publications of the MICROB-PREDICT consortium itself. To receive our newsletter, please subscribe here!
MICROB-PREDICT Publications
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Castelli FA, Rosati G, Moguet C et al. (2021)
Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests
Anal Bioanal Chem: 1-31. Online ahead of print. -
Tranah TH, Edwards LA, Schnabl B et al. (2021)
Targeting the gut-liver-immune axis to treat cirrhosis
Gut. 70: 982-994. -
Trebicka J, Bork P, Krag A, Arumugam M. (2021)
Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure
Nat Rev Gastroenterol Hepatol. 18: pp. 167–180. -
Bader JM, Geyer PE, Müller JB et al. (2020)
Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer’s disease
Mol Syst Biol. 16: e9356 -
Benz F, Bogen A, Praktiknjo M et al. (2020)
Serum levels of bone sialoprotein correlate with portal pressure in patients with liver cirrhosis
PLoS One. 15(4): e0231701. -
Cremonese C, Schierwagen R, Uschner FE et al. (2020)
Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats
Int J Mol Sci. 21(9): 3308. -
Cullaro G, Sharma R, Trebicka J et al. (2020)
Precipitants of Acute-on-Chronic Liver Failure: An Opportunity for Preventative Measures to Improve Outcomes
Liver Transpl. 26(2): 283-293. -
García-Pagán JC, Bosch J, Trebicka J et al. (2020)
Letter: improve survival! Place early pre-emptive TIPSS in high-risk variceal bleeders
Aliment Pharmacol Ther. 52(5): 927-928. -
López-Vicario C, Checa A, Urdangarin A et al. (2020)
Targeted lipidomics reveals extensive changes in circulating lipid mediators in patients with acutely decompensated cirrhosis
J Hepatol. 73(4): 817-828. -
Monteiro S, Grandt J, Uschner FE et al. (2020)
Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation
Gut. 70: 379-387. -
Müller JB, Geyer PE, Colaço AR et al. (2020)
The proteome landscape of the kingdoms of life
Nature. 582: 592–596. -
Praktiknjo M, Simón-Talero M, Römer J et al. (2020)
Total area of spontaneous portosystemic shunts independently predicts hepatic encephalopathy and mortality in liver cirrhosis
J Hepatol. 72(6): 1140-1150. -
Queck A, Bode H, Uschner FE et al. (2020)
Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis
Front Immunol. 11: 354. -
Schierwagen R, Uschner FE, Ortiz C et al. (2020)
The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease
Front Immunol. 11: 1352. -
Torres S, Abdullah Z, Brol MJ et al. (2020)
Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview
Int J Mol Sci. 21(6): 2027. -
Trebicka J, Sundaram V, Moreau R et al. (2020)
Liver Transplantation for Acute-on-Chronic Liver Failure: Science or Fiction?
Liver Transpl. 26(7): 906-915. -
Tyc O, Jansen C, Schierwagen R et al. (2020)
Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease
Liver Transpl. 26: 1652-1657. -
Van Rossum T, Ferretti P, Maistrenko OM et al. (2020)
Diversity within species: interpreting strains in microbiomes
Nat Rev Microbiol. 18: 491–506. -
Zeng-Brouwers J, Pandey S, Trebicka J et al. (2020)
Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases
J Histochem Cytochem. 68(12): 887-906. -
Coenraad M, Papp M, Trebicka J et al. (2019)
MICROB-PREDICT – 15 millió eurós költségvetéssel induló mikrobiom kutatási vizsgálat az Európai Unióban
Central European Journal of Gastroenterology and Hepatology. -5 : 2 (2019), p. 40-42. -CEU-JGH. - 2415-9107 -
Casey S, Schierwagen R, Mak KY et al. (2019)
Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation
J Clin Med. 8(4): 419. -
Klein LM, Chang J, Gu W et al. (2019)
The Development and Outcome of Acute-on-Chronic Liver Failure After Surgical Interventions
Liver Transpl. 26(2): 227-237. -
Korenjak M, Všetičkova V, Credi B. (2019)
ELPA and EU medical research project brochure
Booklet. Relevant pages: 20-23. -
Praktiknjo M, Clees C, Pigliacelli A et al. (2019)
Sarcopenia Is Associated With Development of Acute-on-Chronic Liver Failure in Decompensated Liver Cirrhosis Receiving Transjugular Intrahepatic Portosystemic Shunt
Clin Transl Gastroenterol. 10(4): e00025. -
Queck A, Carnevale R, Uschner FE et al. (2019)
Role of portal venous platelet activation in patients with decompensated cirrhosis and TIPS
Gut. 69: 1535–1536 -
Queck A, Thomas D, Jansen C et al. (2019)
Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis
PLoS One. 14(10): e0222840. -
Schierwagen R, Alvarez-Silva C, Servant F et al. (2019)
Trust is good, control is better: technical considerations in blood microbiome analysis
Gut. 69(7): 1362-1363. -
Torner M, Mangal A, Scharnagl H et al. (2019)
Sex specificity of kidney markers to assess prognosis in cirrhotic patients with TIPS
Liver Int. 40(1): 186-193.
Background Literature
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Trebicka J, Fernandez J, Papp M et al. (2020)
The PREDICT study uncovers three clinical courses in acutely decompensated cirrhosis with distinct pathophysiology.
Journal of Hepatology, DOI: 10.1016/j.jhep.2020.06.013. -
Trebicka J, Fernandez J, Papp M et al. (2020)
PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis
Journal of Hepatology. doi: 10.1016/j.jhep.2020.11.019. -
Alvarez-Silva C, Schierwagen R, Pohlmann A et al. (2019)
Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis.
Front Immunol. 10: Article number 69. -
Clària J, Moreau R, Fenaille F et al. (2019)
Orchestration of Tryptophan-Kynurenine Pathway, Acute Decompensation, and Acute-on-Chronic Liver Failure in Cirrhosis.
Hepatology. 69 (4):1686-1701. -
Fernández J, Prado V, Trebicka J et al. (2019)
Multidrug-resistant bacterial infections in patients with decompensated cirrhosis and with acute-on-chronic liver failure in Europe.
J. Hepatol. 70 (3):398-411. -
Letunic I, Bork P (2019)
Interactive Tree Of Life (iTOL) v4: recent updates and new developments.
Nucleic Acids Res. 47 (1):256-259. -
Niu L, Geyer PE, Wewer Albrechtsen NJ et al. (2019)
Plasma proteome profiling discrovers novel proteins associated with non-alcoholic fatty liver disease.
Mol Syst Biol. 15: Article number 8793. -
Quesada-González D, Sena-Torralba A, Wicaksono WP et al. (2019)
Iridium oxide (IV) nanoparticle-based lateral flow immunoassay.
Biosens Bioelectron. 132: 132-135. -
Romanov N, Kuhn M, Aebersold R et al. (2019)
Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals.
Cell. 177 (5):1308-1318. -
Schmidt TS, Hayward MR, Coelho LP (2019)
Extensive transmission of microbes along the gastrointestinal tract.
Elife. 8: Article number 42693. -
Solà E, Solé C, Ginès P (2019)
New Strategies for the Management of Decompensated Cirrosis: Long-Term Albumin Administration for Everyone?
Hepatology. 69 (5):2289-2291. -
Trebicka J, Amoros A, Pitarch C et al. (2019)
Addressing Profiles of Systemic Inflammation Across the Different Clinical Phenotypes of Acutely Decompensated Cirrhosis.
Front Immunol. 10: Article number 476. -
Schierwagen R, Alvarez-Silva C, Madsen MSA et al. (2018)
Circulating microbiome in blood of different circulatory compartments.
Gut. In print -
Schmidt TSB, Raes J, Bork P (2018)
The human gut microbiome: From association to modulation.
Cell. 172 (6):1198-1215. -
Trebicka J, Reiberger T, Laleman W (2018)
Gut-liver axis links portal hypertension to acute-on-chronic liver failure.
Visc Med. 31 (4):270-275. -
Hackstein CP, Assmus LM, Welz M et al. (2017)
Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis.
Gut. 66 (3): 507-518. -
Arroyo V, Moreau R, Patrick S et al. (2016)
Acute-on-chronic liver failure in cirrhosis
Nature Reviews Disease Primers. 2: Article number 16041. -
Spinella R, Sawhney R and Jalan R (2016)
Albumin in chronic liver disease: structure, functions and therapeutic implications.
Hepatol Int. 10 (1): 124-32. -
Tilg H, Cani PD, Mayer EA (2016)
Gut microbiome and liver diseases.
Gut. 65 (12):2035-2044. -
Qin N, Yang F, Li A et al. (2014)
Alterations of the human gut microbiome in liver cirrhosis.
Nature. 513 (7516):59-64. -
Moreau R, Jalan R, Gines P et al. (2013)
Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis.
Gastroenterology. 144 (7):1426-1437.