Focus on human microbiome to fight liver cirrhosis

22 European institutions join forces in MICROB-PREDICT to improve the prevention and treatment of chronic liver disease (cirrhosis). We aim to identify microbiome-based biomarkers and mechanisms that predict in advance when the body can no longer compensate for the dysfunctional liver (decompensated cirrhosis), when such decompensated cirrhosis will progress to acute-on-chronic liver failure (ACLF), and a patient’s individual treatment response. Based on such biomarkers, we strive to develop novel diagnostic tools for earlier and better patient stratification and to establish personalised and effective treatment strategies.

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MICROB-PREDICT Networking Session at EASL Congress in Amsterdam, NL

Meet the MICROB-PREDICT team during our Networking Session at EASL Congress in Amsterdam, NL, next week to learn more about the project, the virome's role in cirrhosis, how villin-1 and IgA influence gut barrier function, and about the ALB-trial. For a couple of years now, the networking sessions at EASL Congress have been a very popular and interactive format comprised of short talks and direct, informal interaction with attendees at the track hubs in the main congress hall. 

When: Wednesday 7 May, 14:00-14:30

Where: Cirrhosis & Complications Track Hub (Track Hub 4)

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7th GA Meeting in Cologne, Germany from 27-29 January 2025!

A huge thank you to everyone for sharing their latest results and project updates! Together we also celebrated exciting progress in our clinical study: MICROB-PREDICT’s ALB-TRIAL has hit a major milestone in January, with 25% of the targeted 240 patients enrolled across nine active centers in Europe, with more sites joining soon!

And of course, we wrapped it up with some after-work fun, exploring Cologne with a ScienceRallye!

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MICROB-PREDICT project video

Focus on human microbiome to fight liver cirrhosis: 22 European institutions joined forces in January 2019 to improve the prevention and treatment of chronic liver disease (cirrhosis) within the MICROB-PREDICT project. We aim to identify microbiome-based biomarkers and mechanisms that predict in advance when the body can no longer compensate for the dysfunctional liver (decompensated cirrhosis) and decompensated cirrhosis progresses to acute-on-chronic liver failure (ACLF), and individual treatment responses of patients. Coordinator Jonel Trebicka gives a brief overview of the project in this video.

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