For Scientists

Results Videos

Blood-Biomarker to stratify Cirrhosis Patients in the ALB-Trial

In this results video, recorded during the 6th MICROB-PREDICT GA Meeting in Ljubljana, Slovenia, Nikolaj Torp (MD), ALB Trial coordinator and PhD student in the group of Prof. Aleksander Krag at Odense University Hospital (OUH) in Denmark, describes the number of patients, participating countries, study duration and biomarker-based stratification process that cirrhosis patients undergo after being included in MICROB-PREDICT’s albumin trail (ALB Trial).

Metagenomics-Metaproteomics Pipeline for Biomarker Discovery in ACLF 

Peter Treit, a PhD Candidate in Matthias Mann’s group at the Max-Planck Institute of Biochemistry in Munich, Germany, describes the collaborative pan-European data pipeline of the MICROB-PREDICT consortium from bio-sampling to sample analysis (including metagenomics, transcriptomics, and metaproteomics) to assemble a multi-omics biomarker panel for ACLF and to build reliable predictive models for optimal patient stratification and treatment selection. In March 2024, the consortium discussed relevant model parameters at the 6th General Assembly in Ljubljana, Slovenia, models that will be thoroughly tested, benchmarked, and validated before their application in clinical practice.

Multi-Omics Biomarkers for early Identification of Pre-ALCF

Camila Alvarez-Silva (PhD), a postdoctoral researcher in the group of Mani Arumugam at the University of Copenhagen, Denmark, presents the approach and first results of a multi-omics study to identify biomarkers for early identification of PreALCF patients. The video was recorded during the 6th MICROB-PREDICT GA Meeting in Ljubljana, Slovenia, and includes the graphical abstract of the study.

The predictive Role of Immunoglobulins in Gut Barrier Dysfunction

Dávid Tornai (MD, PhD) from the University of Debrecen presents his recent data on the predictive role of immunoglobulins, especially secretory IgA, indicative of gut barrier dysfunction in a prospective patient cohort with cirrhosis and acute decompensation. The video was recorded during the 6th MICROB-PREDICT GA Meeting in Ljubljana, Slovenia, and includes the graphical abstract of the study.

Serum Villin-1, a tell-tale Sign of Gut-Barrier Failure in Cirrhosis

Dávid Tornai (MD, PhD) from the University of Debrecen presents his recent data on serum villin-1 level, a tell-tale sign of gut barrier failure in cirrhotic patients with acute decompensation. The video was recorded during the 6th MICROB-PREDICT GA Meeting in Ljubljana, Slovenia, and includes the graphical abstract of the study.

The Gut Virome and Bacteriophages in decompensated Liver Cirrhosis

Lore Van Espen, PhD candidate in the group of Prof. Jelle Matthijnssens at KU Leuven in Belgium, presents exciting data on the gut virome, particularly on phages (bacteria-infecting viruses) in the gut of patients with decompensated liver cirrhosis. The video was recorded during the 6th MICROB-PREDICT GA Meeting in Ljubljana, Slovenia, and includes the graphical abstract of the study.